The Effect on Gastric Emptying of Telaprevir-Based Triple Therapy for Chronic Hepatitis C Patients | Author : Arata Oyamada, Makoto Arai*, Tomoaki Matumura, Kenichiro Okimoto, Shoko Minemura, Keiko Saito, Daisuke Maruoka, Tomoo Nakagawa, Tatsuo Kanda, Tatsuro Katsuno and Osamu Yokosuka | Abstract | Full Text | Abstract :Aim: We evaluated food intake in telaprevir-based triple therapy (telaprevir, pegylated-interferon, and ribavirin) and its relation to Gastric Emptying (GE).
Methods: 17 patients received telaprevir combined with pegylated interferon plus ribavirin. The GE study was carried out using the 13C-acetate breath test and GE time was expressed as the peak time of 13CO2 excretion (Tmax).
Results: The average food intake was 1,851 ± 91, 1,338 ± 537 and 1,453 ± 537 kcal at 0, 1, and 2 weeks after the start of treatment, respectively, showing a significant decrease compared to that before treatment (p < 0.01 and p <0.05, paired t-test). The averages of Tmax values at 0, 1, and 2 weeks after the start of treatment were 48.4 ± 14.3 min, 56.9 ± 18.4 min and 58.0 ± 19.9 min, respectively. There was a significant difference between baseline and 1 week after the start of treatment (p<0.05, paired t-test). Food intake (kcal) showed a good correlation with the decrease of Tmax values (minutes) (Pearson’s correlation test, r = -0.49, p < 0.05). |
| Beta-(1,3/1,6)-D-glucan Helps to Decrease Opportunistic Infections in Crohn s Disease Patients Treated with Biological Therapy | Author : Batovsky Marian*, Zamborsky Tomas, Radwan Khaled, Desatova Barbora and Kadleckova Barbora | Abstract | Full Text | Abstract :Background: Secondary intercurrent infections in patients with inflammatory bowel disease (IBD) represent a very important problem in daily clinical practice because of their significant contribution to quality of life and work ability. Beta-glucans are known to act as non-specific immunomodulators that exhibit an anti-inflammatory effect as evident in animal and human studies. Imunoglukan P4H® capsules are nutritional supplement containing 100 mg of beta-(1,3/1,6)-D-glucan pleuran isolated from oyster mushroom Pleurotus ostreatus and 100 mg of vitamin C.
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| Colon Lipoma | Author : Néstor Gómez Cuesta*, Stanley Jama, Ernesto Paladines, Jorge Ayòn, Ludwig Álvarez and Jorge Villón | Abstract | Full Text | Abstract :Benign lesions of the colon are infrequent and with a low percentage of appearance. Colon lipomas are in the third place of benign tumors after adenomas and smooth muscle [1,5]. Colonic lipomas are benign non epithelial tumors of soft texture and mesenchymal origin; generally they grow from mature adipocytes.
Lipomas can appear in the entire gastrointestinal tract. They are generally asymptomatic, but when symptomatically, bleeding and obstruction can appear [2,4]. Its clinical diagnosis is difficult, signs and symptoms include abdominal pain, obstruction, lower gastrointestinal bleeding, diarrhea, constipation, and intussusception [5]. These tumors are found in endoscopies, radiological exams, surgical interventions, and autopsies. We present 2 cases of colon lipoma.
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| Implementation and Implication of Ignoring Small Polyps at Colonoscopy | Author : Jana G. Hashash, Ibrahim Hanouneh, Swaytha Ganesh, John Nasr and Robert E. Schoen* | Abstract | Full Text | Abstract :Background and Aim: CT colonography has promoted a new paradigm, that up-to 2 polyps =5mm can be left in-situ and followed. In contrast, endoscopists identify and remove all colorectal polyps, regardless of size. We evaluated whether and how endoscopists might implement a plan of ignoring small polyps in clinical practice.
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| Successful Treatment of Stomal Variceal Bleeding with Percutaneous Injection Sclerotherapy | Author : Takahiro Sato*, Mutsuumi Kimura, Masakatsu Yamaguchi and Takumi Ohmura | Abstract | Full Text | Abstract :Bleeding from ectopic varices is often massive and fatal with portal hypertension, and stomal varices can occur in patients with stoma. We aimed to treat a hepatitis B surface antigen positive 69 year-old male with liver cirrhosis associated hepatocellular carcinoma with bleeding stomal varices using percutaneous injection sclerotherapy. Percutaneous injection sclerotherapy was performed under fluoroscopy using 5% ethanolamine oleate with iopamidol (EOI) with a 25 gauge disposable injection needle; 5ml of 5% EOI were injected gradually. Injection sclerotherapy controlled acute bleeding in this patient without serious complication. The patient experienced no further episodes of bleeding during the 8 months following treatment with percutaneous injection sclerotherapy. In conclusion, percutaneous injection sclerotherapy remains an option for the treatment of patients with bleeding stomal varices.
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| Incarcerated Giant Hiatal Hernia conditioning hearth shock: case report | Author : Medina Andrade Luis Angel | Abstract | Full Text | Abstract :Between the hiatal hernias, the type IV is the less frequent by the great defect, but this type had a high incidence of incarceration (5%), and a mortality rate up to 27%. Case: A female patient of 80 years-old was referred to our hospital by septic shock and abdominal
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